Latest studies have shown that Cannabis oil thc is capable of targeting cancer cells. But before diving into how it works, you’ll need to know the aspects of cancer and how it keeps cancer cells alive.
For each cell, there’s a tree of inter-converting sphingolipids that manages a cell’s life and death. Such collective profiles are known as the “Sphingolipid Rheostat.” If the endogenous ceramide (a metabolite found within the sphingosine-1-phosphate) is relatively high, then cell death would be the result. If ceramide levels happen to be low, then the cell has adequate vitality.
Cell Death with Cannabis Oil THC
Simply put, when THC attaches to the CB1/CB2 of a cancer cell’s cannabinoid receptor site, it increases ceramide synthesis, which leads to cell death. A healthy cell is devoid of ceramide production when THC is present, therefore it’s not influenced by the Cannabinoid.
The cancer cell eventually dies out, not because of the presence of cytotoxic chemicals, but due to a small shift happening within the mitochondria of the cell. In a majority of cells, there’s the cell nucleus, a number of mitochondrial (by the thousands), and other organelles floating in the cytoplasm. The existence of mitochondria is to create energy (ATP) for cellular use.
When ceramide begins to pile up, it turns up the Sphigolipid Rheostat, and increases the permeability of the mitochondria membrane to cytochrome c (a key protein needed for energy synthesis). Cytochrome c is then pushed out of the mitochondria, which then kills the cell’s energy source.
Ceramide also triggers stress within the cancer cell’s nucleus. This generates a protein (p53), which interrupts the mitochondria’s calcium metabolism. If this isn’t enough, ceramide interferes the cellular lysosome (a cell’s own digestive system that distributes nutrients for necessary cell functions). Both ceramide and sphingolipids proactively halt the survival pathways within the cell without any possibility for the cancer cell to survive.
The main key for such process is the ceramide accumulation within the system. This entails ingesting proper CBD and THC amounts steadily over a time period to encourage metabolic pressure on the cancer cell’s death pathway.
Understanding the Endocannabinoid System
How did such pathway come to exist? Why is the body capable of taking a basic enzyme and then utilizing it for healing varying physiological systems? In essence, the endocannabinoid system is present in all animal forms. It’s only a matter of waiting for its paired exocannabinoid activator for it to work.
Our very own endocannabinoid system extends in all nerves and cells. It’s an information messenger that flows between our CNS and immune system. It’s capable of providing immune system micro-management and neuroprotection. This is the main control hub that preserves our well-being.
When the human body gets compromised from injury or illness, it seeks help from the endocannabinoid system to point and direct the immune system for healing. It aids the body by means of a natural process.
CBD usually gravitates to the dense CB2 receptors within the spleen (the body’s immune system home). From there, immune cells are deployed to seek and eradicate cancer cells. Interestingly enough, it’s been proven that CBDs and THCs are capable of destroying cancer cells and bypassing immune system mediums. CBDs and THCs piggyback the lipoxygenase pathway to prevent tumor growth. Basically, the cannabis oil the cannabidiol aids in preserving the body’s own endocannabinoid by suppressing the enzyme from breaking down essential healthy cell processes.